Documentation for genie3
module
bengrn.tools.genie3
Functions:
Name | Description |
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GENIE3 |
GENIE3 Computation of tree-based scores for all putative regulatory links. |
get_link_list |
Gets the ranked list of (directed) regulatory links. |
GENIE3
GENIE3 Computation of tree-based scores for all putative regulatory links.
Parameters: |
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Returns: |
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Source code in bengrn/tools/genie3.py
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get_link_list
Gets the ranked list of (directed) regulatory links.
Args VIM (np.array): Array as returned by the function GENIE3(), in which the element (i,j) is the score of the edge directed from the i-th gene to the j-th gene. gene_names (list[str] optional): List of length p, where p is the number of rows/columns in VIM, containing the names of the genes. The i-th item of gene_names must correspond to the i-th row/column of VIM. When the gene names are not provided, the i-th gene is named Gi. Default is None. regulators (list[str], optional): List containing the names of the candidate regulators. When a list of regulators is provided, the names of all the genes must be provided (in gene_names), and the returned list contains only edges directed from the candidate regulators. When regulators is set to 'all', any gene can be a candidate regulator. Default is 'all'. maxcount (Union[str, int], optional): Writes only the first maxcount regulatory links of the ranked list. When maxcount is set to 'all', all the regulatory links are written. Default is 'all'. file_name (str, optional): Writes the ranked list of regulatory links to the file file_name. Default is None.
Returns pd.Dataframe: The list of regulatory links, ordered according to the edge score. Auto-regulations do not appear in the list. Regulatory links with a score equal to zero are randomly permuted. In the ranked list of edges, each line has format: regulator target gene score of edge
Source code in bengrn/tools/genie3.py
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